In a large bowl, mix together the ground turkey, garlic, thyme, oregano, black pepper, salt, onion powder, bread crumbs, 1/2 cup of the ketchup, Worcestershire sauce, and egg until fully combined.
Grease a 12-cup muffin tin with cooking spray.
Divide the turkey mixture evenly among the muffin cups, pressing down lightly to form a cup shape.
Top each muffin cup with 1 teaspoon of the remaining ketchup.
Bake for 25-30 minutes, or until the internal temperature of the meatloaf muffins reaches 165 degrees F.