In a small mixing bowl, combine the cayenne pepper, paprika, garlic powder, onion powder, salt, and black pepper. Mix well until all the ingredients are evenly distributed.
Transfer the mixture to an airtight container, such as a small jar, and store it in a cool, dry place until ready to use.
To use the cayenne pepper seasoning, sprinkle it onto chicken, fish, or vegetables for an extra kick of heat and flavor.
You can also add the seasoning to sauces, soups, or stews to infuse them with a spicy and smoky undertone.
Remember to use the seasoning sparingly, as cayenne pepper can be very spicy. Adjust the amount according to your taste preferences.